Bis(isobutyl)aluminum chloride → (2-Methoxybenzyl)diisobutylaluminium

HRID 1293492노트

반응식

HRID 1293492 반응식
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=1[CH2:5][Mg]Cl.[Al:12](Cl)([CH2:17][CH:18]([CH3:20])[CH3:19])[CH2:13][CH:14]([CH3:16])[CH3:15]>O1CCCC1>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=1[CH2:5][Al:12]([CH2:17][CH:18]([CH3:20])[CH3:19])[CH2:13][CH:14]([CH3:16])[CH3:15]

참가 물질

4

반응물 2

HCID 15688Bis(isobutyl)aluminum chlorideHCID 178489472HCID 178489472, 화합물

생성물 1

HCID 16688367(2-Methoxybenzyl)diisobutylaluminium

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

150 ml (39 mmol) of (2-methoxybenzyl)magnesium chloride as 0.26 molar solution are added dropwise over the course of 3 hours at 0° C. to 6.83 g (38.7 mmol) of iBu2AlCl in 250 ml of tetrahydrofuran. The mixture is slowly brought to room temperature and stirred at room temperature for 18 h. The solvent is removed under reduced pressure (0.05 mbar), and the residue is suspended in 125 ml of n-pentane. The mixture is subsequently filtered through a D4 frit. After removal of the n-pentane, fractional distillation gives (2-methoxybenzyl)diisobutylaluminium as colourless, viscous liquid having a boiling point of 85° C. at 0.05 mbar.

후처리

  1. customis slowly brought to room temperature
  2. customThe solvent is removed under reduced pressure (0.05 mbar)
  3. filtrationThe mixture is subsequently filtered through a D4 frit
  4. customAfter removal of the n-pentane, fractional distillation

출처 및 근거

ORD 기록
ord-058f60cc42c7472195cce5a8c5c06ca4
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07238757B2

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