3-Ethoxy-4-nitrobenzoic acid → 4-Amino-3-ethoxybenzoic acid

HRID 1293543

반응식

HRID 1293543 반응식
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[N+:13]([O-])=O)[C:7]([OH:9])=[O:8])[CH3:2]>[Pd]>[NH2:13][C:12]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][C:4]=1[O:3][CH2:1][CH3:2]

참가 물질

3

반응물 1

HCID 223975093-Ethoxy-4-nitrobenzoic acid

생성물 1

HCID 223974484-Amino-3-ethoxybenzoic acid수율 92.1%

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

3-Ethoxy-4-nitrobenzoic acid (0.31 g) was treated with 5% palladium on charcoal under an atmosphere of hydrogen (1 bar) for 3 hours. The reaction mixture was filtered and the filtrate was evaporated to leave the product as a beige solid (0.245 g; MS: ES−(M−H) 180).

후처리

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated

출처 및 근거

ORD 기록
ord-c8381f21492a4e5db05019c685a39ad6
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07238811B2

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