Ethanolamine → 5-Bromo-2,4-difluoro-N-(2-hydroxyethyl)benzenesulfonamide

HRID 1293630노트

반응식

HRID 1293630 반응식
[Br:1][C:2]1[C:3]([F:13])=[CH:4][C:5]([F:12])=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:7]=1.[CH2:14]([CH2:16][NH2:17])[OH:15]>>[Br:1][C:2]1[C:3]([F:13])=[CH:4][C:5]([F:12])=[C:6]([S:8]([NH:17][CH2:16][CH2:14][OH:15])(=[O:10])=[O:9])[CH:7]=1

참가 물질

3

반응물 2

HCID 700EthanolamineHCID 27732965-Bromo-2,4-difluorobenzenesulphonyl chloride

생성물 1

HCID 670003525-Bromo-2,4-difluoro-N-(2-hydroxyethyl)benzenesulfonamide수율 100%

실험 절차

Prepared by general procedure III from 5-bromo-2,4-difluorobenzene sulfonyl chloride (1.0 g, 3.4 mmol) and ethanolamine (231 mg, 3.77 mmol) to give the title compound (1.06 g, 100%) as an off-white solid. MS (ISP) 315.8 [(M+H)+].

출처 및 근거

ORD 기록
ord-f479468743f24b40a6d4b9f075d4d22a
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07238808B2

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