4-Nitrophenethyl alcohol → 4-Aminophenethyl alcohol

HRID 129381노트

반응식

HRID 129381 반응식
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([CH2:8][CH2:9][OH:10])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[OH:10][CH2:9][CH2:8][C:7]1[CH:11]=[CH:12][C:4]([NH2:1])=[CH:5][CH:6]=1

참가 물질

4

반응물 1

HCID 74944-Nitrophenethyl alcohol

생성물 1

HCID 669044-Aminophenethyl alcohol수율 87.7%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A slurry of 5 g of 4-nitrophenethyl alcohol, 0.58 g of 10% Pd on carbon in 50 mL of absolute ethanol was shaken overnight under 50 psi of H2. The mixture was filtered and concentrated to yield 3.6 g of 4-(2-hydroxyethyl) aniline, mp 101°-102° C.

후처리

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-84bb3790b7794231954cde8825badf3b
출처 데이터셋
uspto-grants-1995_11
특허 번호
US05468641

반응 노트

불러오는 중…