HCID 67000954, 화합물 → HCID 86608122, 화합물
반응식
[C:1]([C:3]1[CH:4]=[N:5][N:6]2[C:11]([C:12]([F:15])([F:14])[F:13])=[CH:10][C:9]([C:16]3[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=3)=[N:8][C:7]=12)#[CH:2].[CH3:26][C:27]1[CH:32]=[C:31]([CH2:33][NH:34][S:35]([C:38]2[S:39][C:40](Br)=[CH:41][CH:42]=2)(=[O:37])=[O:36])[CH:30]=[C:29]([CH3:44])[N:28]=1>>[CH3:26][C:27]1[CH:32]=[C:31]([CH2:33][NH:34][S:35]([C:38]2[S:39][C:40]([C:2]#[C:1][C:3]3[CH:4]=[N:5][N:6]4[C:11]([C:12]([F:14])([F:13])[F:15])=[CH:10][C:9]([C:16]5[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=5)=[N:8][C:7]=34)=[CH:41][CH:42]=2)(=[O:36])=[O:37])[CH:30]=[C:29]([CH3:44])[N:28]=1참가 물질
3
실험 절차
The title compound was prepared from 3-ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.1) (178 mg, 0.5 mmol) and 5-bromo-thiophene-2-sulfonic acid (2,6-dimethyl-pyridin-4-ylmethyl)-amide (example B.58) (181 mg, 0.5 mmol) according to general procedure II. Obtained as an orange solid (120 mg, 38%). MS (ISN) 634.0 [(M−H)−]; mp 200° C.
출처 및 근거
- ORD 기록
- ord-f3d862709e6b4ee09b47d215c1ca9e7a
- 출처 데이터셋
- uspto-grants-2007_07