Sodium borohydride → 9-Hydroxy-9H-indeno[1,2-b]pyrazin-3(4H)-one

참여 물질

역할	이름	HCID	투입량
반응물	Sodium borohydride	HCID 4311764	—
반응물	9H-Indeno[1,2-b]pyrazine-3,9(4H)-dione	HCID 19035976	—
생성물	9-Hydroxy-9H-indeno[1,2-b]pyrazin-3(4H)-one	HCID 19035984	104.7%

반응 단계

9H-Indeno[1,2-b]pyrazine-3,9(4H)-dione (5.0 g, 25.23 mmol) was reduced with sodium borohydride (1.72 g, 45.5 mmol) as described in example 11. Yield 5.29 g (96%) of the title compound. M.p. 251°-253° C. 1H-NMR (DMSO-d6, δ): 5.32 (d, 1H), 5.92 (d, 1H), 7.47 (m, 2H), 7.64 (m, 1H), 7.8 (m, 1H), 7.9 (s, 1H), 12.5 (s, 1H).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US05468748
출처 데이터셋	uspto-grants-1995_11
ORD ID	ord-d25e5f7fb3b245278ffad42b6d1f0464
출처 메모	uspto-grants-1995_11