Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Ethyl 2-(2-methylpyridin-3-yl)ethanimidoate hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 2-(2-Methylpyridin-3-yl)acetonitrile | HCID 19099286 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Ethyl 2-(2-methylpyridin-3-yl)ethanimidoate hydrochloride | HCID 69411260 | — |
반응 단계
Through a stirred solution of Example 53A (1.7 g, 12.86 mmol), absolute ethanol (0.89 g, 19.35 mmol) and anhydrous methylene chloride (25 ml) was bubbled with hydrogen chloride gas for 20 min. The mixture was allowed to stand overnight in the refrigerator. The product was precipitated with anhydrous ether and filtered to obtain the title compound, which was immediately used in the next step. MS (ESI+) m/z 180 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07241776B2 |
| 출처 데이터셋 | uspto-grants-2007_07 |
| ORD ID | ord-119404a3a29f4697b174a678b01b61f0 |
| 출처 메모 | uspto-grants-2007_07 |