2,4,6-Trihydroxybenzaldehyde → HCID 136380446, 화합물

HRID 1294720노트

반응식

HRID 1294720 반응식
[C:1]1([NH:11][C:12](=[S:15])[NH:13][NH2:14])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[OH:16][C:17]1[CH:24]=[C:23]([OH:25])[CH:22]=[C:21]([OH:26])[C:18]=1[CH:19]=O>C(O)(=O)C>[C:1]1([NH:11][C:12](=[S:15])[NH:13][N:14]=[CH:19][C:18]2[C:17]([OH:16])=[CH:24][C:23]([OH:25])=[CH:22][C:21]=2[OH:26])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 2

HCID 680992,4,6-TrihydroxybenzaldehydeHCID 2760175N-(Naphthalen-1-yl)hydrazinecarbothioamide

생성물 1

HCID 136380446HCID 136380446, 화합물수율 54%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A solution of 4-(naphth-1-yl)thiosemicarbazide (572 mg, 2.63 mmol) and 2,4,6-trihydroxybenzaldehyde (405 mg, 2.63 mmol) in acetic acid (5 mL) was heated under reflux for 20 min, then cooled. The precipitate was filtered, washed (acetic acid) and dried to give the title compound (445 mg, 54%) as a solid. MS (ES+) m/e 354 [M+H]+.

후처리

  1. temperatureunder reflux for 20 min
  2. temperaturecooled
  3. filtrationThe precipitate was filtered
  4. washwashed (acetic acid)
  5. customdried

출처 및 근거

ORD 기록
ord-5d878955377d46e0b30124adea33c3aa
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07241783B2

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