Cyclohexene → 4-[2-allyl-7-(trifluoromethyl)-2H-indazol-3-yl]-3-methylphenol
반응식
[CH2:1]([N:4]1[C:12]([C:13]2[CH:18]=[CH:17][C:16]([O:19]C)=[CH:15][C:14]=2[CH3:21])=[C:11]2[C:6]([C:7]([C:22]([F:25])([F:24])[F:23])=[CH:8][CH:9]=[CH:10]2)=[N:5]1)[CH:2]=[CH2:3].B(Br)(Br)Br.C1CCCCC=1>>[CH2:1]([N:4]1[C:12]([C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][C:14]=2[CH3:21])=[C:11]2[C:6]([C:7]([C:22]([F:25])([F:24])[F:23])=[CH:8][CH:9]=[CH:10]2)=[N:5]1)[CH:2]=[CH2:3]참가 물질
4
실험 절차
Prepared according to Method D step C from 2-allyl-3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-2H-indazole (0.043 g, 0.124 mmol), boron tribromide (0.05 mL, 0.52 mmol) and 1.0 mL of cyclohexene to give the product (0.033 g) as a white solid.
후처리
- customPrepared