Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylhydrazine → 3-(4-Chlorophenyl)-1-Methyl-1H-Pyrazol-5-Amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylhydrazine | HCID 6061 | — |
| 반응물 | 4-Chlorobenzoylacetonitrile | HCID 138308 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(4-Chlorophenyl)-1-Methyl-1H-Pyrazol-5-Amine | HCID 2735304 | 46% |
반응 단계
A solution of 3-(4-Chloro-phenyl)-3-oxo-propionitrile (1.8 g, 10 mmol) and N-Methylhydrazine (1 mL, excess) in EtOH (30 mL) was stirred to reflux 3 hours. After cooling the precipitate was filtered off, to give the title compound (950 mg, 4.6 mmol) as white crystals in a 46% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07241793B2 |
| 출처 데이터셋 | uspto-grants-2007_07 |
| ORD ID | ord-5b329b88a7da4a85ba665c7e2a106894 |
| 출처 메모 | uspto-grants-2007_07 |