Hydrogen Peroxide → HCID 69508634, 화합물

HRID 1295738노트

반응식

HRID 1295738 반응식
[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][S:12][CH3:13])[CH:5]=1.[OH:14]O>C(O)(=O)C.C(Cl)Cl.C([O-])([O-])=O.[K+].[K+]>[CH3:13][S:12]([CH2:11][O:10][C:6]1[CH:5]=[C:4]([CH:9]=[CH:8][CH:7]=1)[CH2:3][NH:2][CH3:1])=[O:14]

참가 물질

6

반응물 2

HCID 784Hydrogen PeroxideHCID 69507792HCID 69507792, 화합물

생성물 1

HCID 69508634HCID 69508634, 화합물

시약·촉매·용매 3

HCID 176Acetic Acid용매HCID 6344Dichloromethane용매HCID 11430Potassium Carbonate용매

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온도
0 °C

실험 절차

Compound from step 3 (592 mg, 3.00 mmol) was dissolved in glacial acetic acid (4 mL) and cooled to 0° C. H2O2 (0.34 mL, 3.00 mmol) was added drop-wise. The mixture was allowed to stir for 6 h. The mixture was then diluted with CH2Cl2 and neutralized with K2CO3. The solids were filtered off. The filtrate was dried over Na2SO4 and concentrated in vacuo to give 640 mg (quant) of a yellow crystalline solid.

후처리

  1. filtrationThe solids were filtered off
  2. dry with materialThe filtrate was dried over Na2SO4
  3. concentrationconcentrated in vacuo
  4. customto give 640 mg (quant) of a yellow crystalline solid

출처 및 근거

ORD 기록
ord-b63a465c593a4d1fa77a5b9350631b67
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07244738B2

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