참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 8-Aminooctanoic acid | HCID 66085 | — |
| 생성물 | Methyl 8-aminooctanoate hydrochloride | HCID 12878164 | — |
반응 단계
0.7 cm3 of thionyl chloride is added to a solution of 1 g of 8-aminooctanoic acid in 40 cm3 of methanol at a temperature in the region of -20° C. and stirring is maintained for 12 hours at a temperature in the region of 20° C. The solvent is removed under reduced pressure (2.7 kPa) at a temperature in the region of 35° C. 1.48 g of methyl 8-aminooctanoate hydrochloride is thus obtained in the form of a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05468888 |
|---|
| 출처 데이터셋 | uspto-grants-1995_11 |
|---|
| ORD ID | ord-678f33cd827b41fe9bb0c6f946066656 |
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| 출처 메모 | uspto-grants-1995_11 |
|---|
