반응식
S(Cl)([Cl:3])=O.[NH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14].[CH3:16]O>>[ClH:3].[NH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([O:15][CH3:16])=[O:14]참가 물질
4
반응 조건
- 온도
- 20 °C
실험 절차
0.7 cm3 of thionyl chloride is added to a solution of 1 g of 8-aminooctanoic acid in 40 cm3 of methanol at a temperature in the region of -20° C. and stirring is maintained for 12 hours at a temperature in the region of 20° C. The solvent is removed under reduced pressure (2.7 kPa) at a temperature in the region of 35° C. 1.48 g of methyl 8-aminooctanoate hydrochloride is thus obtained in the form of a white solid.
후처리
- customThe solvent is removed under reduced pressure (2.7 kPa) at a temperature in the region of 35° C
출처 및 근거
- ORD 기록
- ord-678f33cd827b41fe9bb0c6f946066656
- 출처 데이터셋
- uspto-grants-1995_11
- 특허 번호
- US05468888
연결된 노트
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