Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Carbomethoxy-4-(3-methoxyphenyl)-3-butenoic acid → 3-Carbomethoxy-4-(3-methoxyphenyl)butanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Carbomethoxy-4-(3-methoxyphenyl)-3-butenoic acid | HCID 589607 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 3-Carbomethoxy-4-(3-methoxyphenyl)butanoic acid | HCID 10658447 | 83.1% |
반응 단계
A solution of 21.1 g (84 mmol) of 3-carbomethoxy-4-(3-methoxyphenyl)-3-butenoic acid in 100 ml of acetic acid with 2.11 g of 10% Pd on carbon is shaken under H2 atmosphere until H2 uptake ceases (approximately 4 hours). This is filtered through celite and the filtrate concentrated in vacuo several times from toluene to afford 17.6 g of 3-carbomethoxy-4-(3-methoxyphenyl)butanoic acid in the form of a yellow oil which is used directly in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05468898 |
| 출처 데이터셋 | uspto-grants-1995_11 |
| ORD ID | ord-a131f54ab91a46f0a140d8f163f67720 |
| 출처 메모 | uspto-grants-1995_11 |