L-(+)-Cysteine → HCID 14881540, 화합물

HRID 129727

반응식

HRID 129727 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)=O.[NH2:15][C@H:16]([C:19]([OH:21])=[O:20])[CH2:17][SH:18]>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)[NH:15][CH:16]([C:19]([OH:21])=[O:20])[CH2:17][S:18]1

참가 물질

4

반응물 2

HCID 5862L-(+)-CysteineHCID 88065Bis(2-pyridyl) ketone

생성물 1

HCID 14881540HCID 14881540, 화합물수율 11%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 3.68 g of di-2-pyridyl ketone, 2.42 g of L-cysteine, 25 ml of ethanol was refluxed for 3.5 hours. After allowing the mixture to cool, the insoluble matter was filtered off, and the filtrate was concentrated to dryness under reduced pressure. The residue was washed in sequence with ethyl acetate and ether to give 0.63 g of 2,2-di(2-pyridyl)-thiazolidine-4-carboxylic acid.

후처리

  1. temperaturewas refluxed for 3.5 hours
  2. temperatureto cool
  3. filtrationthe insoluble matter was filtered off
  4. concentrationthe filtrate was concentrated to dryness under reduced pressure
  5. washThe residue was washed in sequence with ethyl acetate and ether

출처 및 근거

ORD 기록
ord-fbee9d5e5b41400f9f3691bf051546d4
출처 데이터셋
uspto-grants-1995_11
특허 번호
US05470851

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