1,3-dimethyl-1H-indole-2-carbaldehyde → HCID 22139054, 화합물

HRID 1297413노트

반응식

HRID 1297413 반응식
BrC1C=C[C:5](NCC(OC)=O)=[N:6]C=1.[Cl:14][C:15]1[CH:23]=[CH:22][CH:21]=[C:20]2[C:16]=1[C:17]([CH:25]=O)=[CH:18][N:19]2[CH3:24].CN1C2C(=CC=CC=2)C(C)=C1C=O>>[Cl:14][C:15]1[CH:23]=[CH:22][CH:21]=[C:20]2[C:16]=1[C:17]([CH2:25][NH:6][CH3:5])=[CH:18][N:19]2[CH3:24]

참가 물질

4

반응물 3

HCID 27714681,3-dimethyl-1H-indole-2-carbaldehydeHCID 22139049Methyl 2-((5-bromopyridin-2-yl)amino)acetateHCID 221391304-chloro-1-methyl-1H-indole-3-carboxaldehyde

생성물 1

HCID 22139054HCID 22139054, 화합물수율 78%

실험 절차

According to the procedure of Preparation 13 (c), except substituting 4-chloro-1-methyl-1H-indole-3-carboxaldehyde for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (1.75 g, 78%) was obtained as a yellow solid: MS (ES) m/e 209.0 (M+H)+.

출처 및 근거

ORD 기록
ord-0f6ef02dd12e42cab600d94b51939788
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07250424B2

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