N-3-Bromopropylphthalimide → 4-[Bis(4-fluorophenyl)methylene]-1-(3-phthalimidopropyl)piperidine

HRID 129765

반응식

HRID 129765 반응식
Br[CH2:2][CH2:3][CH2:4][N:5]1[C:9](=[O:10])[C:8]2=[CH:11][CH:12]=[CH:13][CH:14]=[C:7]2[C:6]1=[O:15].[F:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]([C:30]2[CH:35]=[CH:34][C:33]([F:36])=[CH:32][CH:31]=2)=[C:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)=[CH:19][CH:18]=1>>[F:36][C:33]1[CH:34]=[CH:35][C:30]([C:23]([C:20]2[CH:19]=[CH:18][C:17]([F:16])=[CH:22][CH:21]=2)=[C:24]2[CH2:29][CH2:28][N:27]([CH2:2][CH2:3][CH2:4][N:5]3[C:9](=[O:10])[C:8]4=[CH:11][CH:12]=[CH:13][CH:14]=[C:7]4[C:6]3=[O:15])[CH2:26][CH2:25]2)=[CH:31][CH:32]=1

참가 물질

3

반응물 2

HCID 21611N-3-BromopropylphthalimideHCID 27244364-(Bis(4-fluorophenyl)methylene)piperidine

생성물 1

HCID 193703024-[Bis(4-fluorophenyl)methylene]-1-(3-phthalimidopropyl)piperidine수율 97%

실험 절차

The title compound was prepared in a yield of 97% in a similar manner to that described in Preparation 1' by reacting N-(3-bromopropyl)phthalimide and 4-[bis(4-fluorophenyl)methylene]piperidine.

후처리

  1. customdescribed in Preparation 1'

출처 및 근거

ORD 기록
ord-afc2303c18c94815a5012832f8221b67
출처 데이터셋
uspto-grants-1995_11
특허 번호
US05470851

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