Cesium carbonate → 2-{4'-[(3aR,6aR)-5-Methylhexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl]biphenyl-4-yl}-4,5-dihydropyridazin-3(2H)-one

반응식

Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([N:14]3[C:19](=[O:20])[CH2:18][CH2:17][CH:16]=[N:15]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.Cl.Cl.[CH3:23][N:24]1[CH2:31][C@@H:30]2[C@@H:26]([NH:27][CH2:28][CH2:29]2)[CH2:25]1.C(=O)([O-])[O-].[Cs+].[Cs+].C1(P(C2CCCCC2)C2C=CC=CC=2C2C=CC=CC=2N(C)C)CCCCC1>[O-]S(C(F)(F)F)(=O)=O.[Ag+].C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd].C1(C)C=CC=CC=1>[CH3:23][N:24]1[CH2:31][C@@H:30]2[C@@H:26]([N:27]([C:2]3[CH:7]=[CH:6][C:5]([C:8]4[CH:13]=[CH:12][C:11]([N:14]5[C:19](=[O:20])[CH2:18][CH2:17][CH:16]=[N:15]5)=[CH:10][CH:9]=4)=[CH:4][CH:3]=3)[CH2:28][CH2:29]2)[CH2:25]1