1,3-dimethyl-4,5,6,7-tetrahydro-1H-indene → Lithium 1,3-dimethyl-4,5,6,7-tetrahydro-1H-inden-1-ide

HRID 129983노트

반응식

HRID 129983 반응식
[CH3:1][C:2]1[C:3]2[CH2:4][CH2:5][CH2:6][CH2:7][C:8]=2[CH:9]([CH3:11])[CH:10]=1.[Li:12]CCCC>CCCCC>[CH3:1][C-:2]1[C:3]2[CH2:4][CH2:5][CH2:6][CH2:7][C:8]=2[C:9]([CH3:11])=[CH:10]1.[Li+:12]

참가 물질

4

반응물 2

HCID 129801691,3-dimethyl-4,5,6,7-tetrahydro-1H-indeneHCID 178418339Butyllithium

생성물 1

HCID 23721395Lithium 1,3-dimethyl-4,5,6,7-tetrahydro-1H-inden-1-ide수율 97%

시약·촉매·용매 1

HCID 8003Pentane용매

실험 절차

7,9 dimethylbicyclo-[4.3.0]-nona-1(6),7-diene (5.0 g, 33.5 mmol) was added to 100 mL of pentane. To this solution nBuLi (2.7M, 13 mL) was added dropwise, and the mixture was stirred for 12 hours. The resulting white precipitate was collected via filtration, washed with pentane and dried under reduced pressure to give 5.02 g (97 percent) of product.

후처리

  1. filtrationThe resulting white precipitate was collected via filtration
  2. washwashed with pentane
  3. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-dcdf309000d9440f88acc07b8ccba5ab
출처 데이터셋
uspto-grants-1995_11
특허 번호
US05470993

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