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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1301650생성일: 2026년 10월 25일

Morpholine → 4-(4-Trifluoromethylphenyl)morpholine

https://huagongshe.com/reaction/1301650

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참여 물질

역할이름HCID투입량
반응물MorpholineHCID 8083—
반응물Benzene, 1-bromo-4-(trifluoromethyl)-HCID 67872—
시약Lithium trimethylsilanolateHCID 74821—
촉매HCID 178526102HCID 178526102—
용매DiglymeHCID 8150—
생성물CaffeineHCID 2519—
생성물4-(4-Trifluoromethylphenyl)morpholineHCID 109333100%
생성물4-(3-(Trifluoromethyl)phenyl)morpholineHCID 154202990%

반응 조건

온도60 °C

출처 및 근거

DOI10.1021/jacs.6c05959
출처 데이터셋High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
ORD IDord-f5f49971f6f94195a214db0e7707e81f
출처 메모High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions