2-Acetylbenzofuran → 1-(2-Benzofuryl)-4,4,5,5,5-pentafluoro-1,3-pentanedione

HRID 130299

반응식

HRID 130299 반응식
[C:1]([C:4]1[O:5][C:6]2[CH:12]=[CH:11][CH:10]=[CH:9][C:7]=2[CH:8]=1)(=[O:3])[CH3:2].[F:13][C:14]([F:24])([F:23])[C:15]([F:22])([F:21])[C:16](OCC)=[O:17]>>[O:5]1[C:6]2[CH:12]=[CH:11][CH:10]=[CH:9][C:7]=2[CH:8]=[C:4]1[C:1](=[O:3])[CH2:2][C:16](=[O:17])[C:15]([F:22])([F:21])[C:14]([F:24])([F:23])[F:13]

참가 물질

3

반응물 2

HCID 154352-AcetylbenzofuranHCID 67928Propanoic acid, 2,2,3,3,3-pentafluoro-, ethyl ester

생성물 1

HCID 101495991-(2-Benzofuryl)-4,4,5,5,5-pentafluoro-1,3-pentanedione

실험 절차

The compound was synthesized according to example 1 using 2-acetylbenzofuran and ethyl pentafluoropropionate as starting materials. The product was crystallized from petroleum ether. 1H NMR (CDCl3): 6.75 (s, 1 H); 7.35 (ddd, 1H, J=0.9 & 7.1 & 7.9 Hz); 7.51 (ddd, 1H, J=1.3 & 7.1 & 8.4 Hz); 7.58-7.60 (m, 1 H); 7.67 (d, 1H, J=0.9 Hz); 7.71-7.73 (m, 1 H). IR (film): 1614 (C═O); 1211, 1200 (C—F).

후처리

  1. customThe compound was synthesized
  2. customThe product was crystallized from petroleum ether

출처 및 근거

ORD 기록
ord-6dbe56fcc3384380ac36ed4731f1fff4
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07381567B2

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