2-Amino-6-nitrobenzothiazole → 2,6-Benzothiazolediamine

HRID 130339

반응식

HRID 130339 반응식
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.[H][H]>CO.[Pd]>[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:5]=2[N:6]=1

참가 물질

5

반응물 2

HCID 227042-Amino-6-nitrobenzothiazoleHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 215042,6-Benzothiazolediamine수율 99.3%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매2회

실험 절차

2-Amino-6-nitrobenzothiazole (500 mg, 2.56 mmol) was dissolved in methanol (20 mL) and 10% palladium on carbon (50 mg) was added as a slurry in methanol (1 mL). The atmosphere was replaced with hydrogen and the suspension was stirred overnight. The catalyst was removed by suction filtration and the solvent evaporated to afford 2,6-diaminobenzothiazole (420 mg, 99%) as a pale yellow solid.

후처리

  1. customThe catalyst was removed by suction filtration
  2. customthe solvent evaporated

출처 및 근거

ORD 기록
ord-2bb820c6c6b84c03b05572fcc80c66e2
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07381734B2

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