2-Amino-6-nitrobenzothiazole → 2,6-Benzothiazolediamine
반응식
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.[H][H]>CO.[Pd]>[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:5]=2[N:6]=1참가 물질
5
실험 절차
2-Amino-6-nitrobenzothiazole (500 mg, 2.56 mmol) was dissolved in methanol (20 mL) and 10% palladium on carbon (50 mg) was added as a slurry in methanol (1 mL). The atmosphere was replaced with hydrogen and the suspension was stirred overnight. The catalyst was removed by suction filtration and the solvent evaporated to afford 2,6-diaminobenzothiazole (420 mg, 99%) as a pale yellow solid.
후처리
- customThe catalyst was removed by suction filtration
- customthe solvent evaporated
출처 및 근거
- ORD 기록
- ord-2bb820c6c6b84c03b05572fcc80c66e2
- 출처 데이터셋
- uspto-grants-2008_06
- 특허 번호
- US07381734B2
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