N-(3,4-Dichlorophenyl)thiourea → {3-[2-(3,4-Dichloro-phenylamino)-thiazol-4-yl]-phenoxy}-phenyl-acetic acid methyl ester

HRID 130356

반응식

HRID 130356 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([NH:9][C:10]([NH2:12])=[S:11])[CH:5]=[CH:6][C:7]=1[Cl:8].[CH3:13][O:14][C:15](=[O:34])[CH:16]([O:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([C:30](=O)[CH2:31]Br)[CH:25]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:13][O:14][C:15](=[O:34])[CH:16]([O:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([C:30]2[N:12]=[C:10]([NH:9][C:4]3[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=3)[S:11][CH:31]=2)[CH:25]=1)[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

참가 물질

3

반응물 2

HCID 710776N-(3,4-Dichlorophenyl)thioureaHCID 86607372[3-(2-Bromo-acetyl)-phenoxy]-phenyl-acetic acid methyl ester

생성물 1

HCID 86607371{3-[2-(3,4-Dichloro-phenylamino)-thiazol-4-yl]-phenoxy}-phenyl-acetic acid methyl ester

실험 절차

{3-[2-(3,4-Dichloro-phenylamino)-thiazol-4-yl]-phenoxy}-phenyl-acetic acid methyl ester was prepared as per procedure I using (3,4-dichloro-phenyl)-thiourea and [3-(2-Bromo-acetyl)-phenoxy]-phenyl-acetic acid methyl ester using Procedure I.

출처 및 근거

ORD 기록
ord-b7b1dbc5931c4f5abd46719be806935f
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07381736B2

연결된 노트

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