Sulfuric Acid → 4,4'-Difluorobenzophenone

HRID 1304

반응식

HRID 1304 반응식
[CH:1]1[C:6]([CH2:7][C:8]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=2)=[CH:5][CH:4]=[C:3]([F:15])[CH:2]=1.S(=O)(=O)(O)[OH:17]>O=[Mn]=O.O>[F:15][C:3]1[CH:2]=[CH:1][C:6]([C:7]([C:8]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=2)=[O:17])=[CH:5][CH:4]=1

참가 물질

5

반응물 2

HCID 1118Sulfuric AcidHCID 960941,1'-Methylenebis[4-fluorobenzene]

생성물 1

HCID 95824,4'-Difluorobenzophenone수율 54%

시약·촉매·용매 2

HCID 14801Manganese dioxide촉매HCID 962Water용매

실험 절차

The procedure of Example 2 is used except that the 4,4'-difluorodiphenylmethane, water, and sulfuric acid are first mixed, then heated before the MnO2 is added. The yield is 54% 4,4'-difluorobenzophenone that is 95% pure.

후처리

  1. additionare first mixed
  2. additionis added

출처 및 근거

ORD 기록
ord-dcc5f15a2f3f46578b2a4b1538a1f0d4
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723676

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