Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → 3-(2,4-Difluorophenyl)acrylic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 2,4-Difluorobenzaldehyde | HCID 73770 | — |
| 생성물 | 3-(2,4-Difluorophenyl)acrylic Acid | HCID 603502 | 77% |
반응 단계
A disadvantage here is the high reaction temperature needed, the unsatisfactory yield and the difficult accessibility of the compounds of the formula (I). Monatshefte der Chemie 90, 680 (1959) describes the reaction of 2,4-difluorobenzaldehyde with acetic anhydride at 180° C., 2,4-difluoro-cinnamic acid being obtained in a 77% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07381832B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-713f7e8e136d41799a23ae377085f383 |
| 출처 메모 | uspto-grants-2008_06 |