Thionyl Chloride → 4,6-Dichloro-1-indanone

HRID 130609노트

반응식

HRID 130609 반응식
S(Cl)(Cl)=O.[Cl:5][C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:7]=1[CH2:13][CH2:14][C:15]([OH:17])=O>C(Cl)Cl>[Cl:5][C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[C:8]2[C:7]=1[CH2:13][CH2:14][C:15]2=[O:17]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 27409153-(2,4-Dichlorophenyl)propanoic acid

생성물 1

HCID 122065184,6-Dichloro-1-indanone

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Thionyl chloride (36.9 g) was added dropwise at 40° C. to a solution of 3-(2,4-di-chlorophenyl)propionic acid (43.8 g) in methylene chloride (200 ml).

출처 및 근거

ORD 기록
ord-3ce158dfd91e477db2c43cb99e7a6621
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07381832B2

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