Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylpropanolamine → (1R,2S)-1-[1-(4-fluorophenyl)-6-methyl-indazol-5-yl]oxy-1-phenyl-propan-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylpropanolamine | HCID 10297 | — |
| 반응물 | 1-(4-Fluorophenyl)-5-iodo-6-methylindazole | HCID 59339914 | — |
| 생성물 | (1R,2S)-1-[1-(4-fluorophenyl)-6-methyl-indazol-5-yl]oxy-1-phenyl-propan-2-amine | HCID 59339631 | — |
반응 단계
Prepared as described in Example 1 from (1R,2S)-2-amino-1-phenylpropan-1-ol (257 mg, 1.70 mmol), and 1-(4-fluorophenyl)-5-iodo-6-methylindazole (200 mg, 0.57 mmol). Yield 169 mg (79%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728030B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-fb9b9bdeae74416bbcb78466dbed8181 |
| 출처 메모 | uspto-grants-2010_06 |