Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-Dimethylethylenediamine → N,N-dimethyl-N'-(5-nitropyridin-2-yl)ethane-1,2-diamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-Dimethylethylenediamine | HCID 66053 | — |
| 반응물 | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| 반응물 | Ethane, azido- | HCID 79118 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | N,N-dimethyl-N'-(5-nitropyridin-2-yl)ethane-1,2-diamine | HCID 3696952 | — |
반응 단계
To a solution of 2-chloro-5-nitropyridine 106-A and EtN3 (4.7 g, 46.5 mmol) in CH3CN (150 ml) was added N,N-dimethylethlenediamine 106-B (4.1 g, 46.5 mmol). The solution was stirred at room temperature for 3 hours, extracted with EtOAc, washed (brine), dried(MgSO4) and concentrated to give N,N-dimethyl-N′-(5-nitropyridin-2-yl)ethane-1,2-diamine 106-C (5.2 g) as a yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07381824B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-3632a75afb1e4d6bab2873d1474fea9c |
| 출처 메모 | uspto-grants-2008_06 |