3-Phenoxy-1,2-propanediol → Phenoxyacetaldehyde

HRID 13077

반응식

HRID 13077 반응식
I([O-])(=O)(=O)=O.[Na+].[O:7]([CH2:14][CH:15]([OH:18])CO)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>ClCCl>[O:7]([CH2:14][CH:15]=[O:18])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

4

반응물 2

HCID 108573-Phenoxy-1,2-propanediolHCID 23667635Sodium periodate

생성물 1

HCID 75033Phenoxyacetaldehyde수율 100%

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

Sodium periodate (0.65 M in water, 20 mL) was added to a vigorously stirred suspension of silica gel (20 g) in dichloromethane (160 mL), followed by a solution of 3-phenoxy-1,2-propanediol (1.68 g, 10.0 mmol) in dichloromethane (20 mL). After stirring for 10 min the mixture was filtered and the filtrate was concentrated to give the subtitle compound (1.36 g, 100%).

후처리

  1. filtrationwas filtered
  2. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-1e1e15121926420891672153556960f2
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728030B2

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