Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Picolinic acid → N-((1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-yl)picolinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Picolinic acid | HCID 1018 | — |
| 반응물 | (1R,2S)-1-(1-(4-fluorophenyl)indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amine | HCID 59339733 | — |
| 생성물 | N-((1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-yl)picolinamide | HCID 25013325 | — |
반응 단계
Prepared as described in Example 83 using (1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amine (6a, 28 mg, 0.07 mmol) and picolinic acid (9 mg, 0.07 mmol). Yield 14 mg (39%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728030B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-3e7564df49bd4dc8b2bebd47926b51e6 |
| 출처 메모 | uspto-grants-2010_06 |