(S)-2-(Boc-Amino)-N-methoxy-n-methylbutyramide → (S)-tert-butyl 1-oxo-1-phenylbutan-2-ylcarbamate

HRID 13112노트

반응식

HRID 13112 반응식
[O:1]=[C:2]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C@@H:3]([NH:7][C:8](=[O:14])[O:9][C:10]([CH3:13])([CH3:12])[CH3:11])[CH2:4][CH2:5]C.CON(C)C(=O)[C@@H](NC(=O)OC(C)(C)C)CC>>[O:1]=[C:2]([C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)[C@@H:3]([NH:7][C:8](=[O:14])[O:9][C:10]([CH3:12])([CH3:13])[CH3:11])[CH2:4][CH3:5]

참가 물질

3

반응물 2

HCID 10422029(S)-2-(Boc-Amino)-N-methoxy-n-methylbutyramideHCID 59339674(S)-tert-butyl 1-oxo-1-phenylpentan-2-ylcarbamate

생성물 1

HCID 11346070(S)-tert-butyl 1-oxo-1-phenylbutan-2-ylcarbamate

실험 절차

was synthesised in the same way as (91c) from (S)-tert-butyl 1-(methoxy(methyl)amino)-1-oxobutan-2-ylcarbamate (95d, 250 mg, 1.02 mmol).

출처 및 근거

ORD 기록
ord-2a3e8bd68fa241d19cde6c24a66c1060
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728030B2

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