(S)-2-((tert)-Butoxycarbonyl)amino)butanoic acid → (S)-2-(Boc-Amino)-N-methoxy-n-methylbutyramide

HRID 13113

반응식

HRID 13113 반응식
[CH3:1][O:2][N:3]([CH3:18])[C:4](=[O:17])[C@@H:5]([NH:9][C:10](=[O:16])[O:11][C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:6][CH2:7]C.C(OC(N[C@@H](CC)C(O)=O)=O)(C)(C)C>>[CH3:1][O:2][N:3]([CH3:18])[C:4](=[O:17])[C@@H:5]([NH:9][C:10](=[O:16])[O:11][C:12]([CH3:13])([CH3:15])[CH3:14])[CH2:6][CH3:7]

참가 물질

3

반응물 2

HCID 2755934(S)-2-((tert)-Butoxycarbonyl)amino)butanoic acidHCID 9992774(S)-tert-butyl 1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate

생성물 1

HCID 10422029(S)-2-(Boc-Amino)-N-methoxy-n-methylbutyramide

실험 절차

was synthesised in the same way as (91d) from commercially available (2S)-2-[(tert-butoxycarbonyl)amino]butanoic acid (0.935 g, 4.60 mmol).

출처 및 근거

ORD 기록
ord-9d9db886bc5e4421b3043558471c1a63
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728030B2

연결된 노트

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