Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 131209생성일: 2026년 10월 25일
Hydrochloric Acid → 1-(4-Methoxy-benzyl)-2-phenoxymethyl-1H-benzoimidazole-5-carboxylic acid allyl ester
https://huagongshe.com/reaction/131209
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 4-[tert-Butoxycarbonyl-(4-trifluoromethoxy-benzyl)-amino]-3-(2-phenoxy-acetylamino)-benzoic acid allyl ester | HCID 68466940 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 1-(4-Methoxy-benzyl)-2-phenoxymethyl-1H-benzoimidazole-5-carboxylic acid allyl ester | HCID 68464256 | — |
반응 단계
Crude 4-[tert-butoxycarbonyl-(4-trifluoromethoxy-benzyl)-amino]-3-(2-phenoxy-acetylamino)-benzoic acid allyl ester was dissolved in methanol and 4N HCl in dioxan added. The reaction was stirred at 40° C. for 16 h. The crude material was purified via reversed phase preparative HPLC. MS(ISP): 483.3 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07384945B2 |
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| 출처 데이터셋 | uspto-grants-2008_06 |
|---|
| ORD ID | ord-a9bce4f8a9ab40b595f50233bacb5888 |
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| 출처 메모 | uspto-grants-2008_06 |
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