참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Stannous Chloride | HCID 24479 | — |
| 반응물 | 5-Isopropyl-2-(2-nitro-phenylamino)-benzonitrile | HCID 21093536 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Isopropyl-5H-dibenzo[b,e][1,4]diazepin-11-ylamine hydrochloride | HCID 21093486 | — |
반응 단계
Combine 5-isopropyl-2-(2-nitro-phenylamino)-benzonitrile (4.54 g, 16.1 mmol) and tin (II) chloride (10.92 g, 48.4 mmol) in 65.0 mL of 5N HCl solution and 65.0 mL of ethanol. Heat this mixture at 86° C. for 18 hours. Chilling the mixture precipitates the title compound as 4.22 g of a yellow solid: mp>250° C.; mass spectrum (ion spray): m/z=252 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07384934B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_06 |
|---|
| ORD ID | ord-2fe6f9243a0e4cf0a9d651c057014da0 |
|---|
| 출처 메모 | uspto-grants-2008_06 |
|---|
