Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Methylthiophene-2-carboxylic acid → HCID 59339741, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Methylthiophene-2-carboxylic acid | HCID 74713 | — |
| 반응물 | (1R,2S)-1-(1-(4-fluorophenyl)indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amine | HCID 59339733 | — |
| 생성물 | HCID 59339741 | HCID 59339741 | — |
반응 단계
Prepared as described in Example 105 using (1R,2S)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(3-methoxyphenyl)propan-2-amine (6a, 39 mg, 100 μmol) and 5-methyl-2-thiophenecarboxylic acid (28 mg, 200 μmol). Yield 42 mg (81%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728030B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-b3a5dfe6309448af93f14ac639021ccc |
| 출처 메모 | uspto-grants-2010_06 |