N-(2-Methoxy-5-nitrobenzyl)acetamide → HCID 58629454, 화합물

HRID 131667노트

반응식

HRID 131667 반응식
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][C:4]=1[CH2:5][NH:6][C:7](=[O:9])[CH3:8].[H][H]>[Pd].C(O)C>[C:7]([NH:6][CH2:5][C:4]1[CH:10]=[C:11]([CH:12]=[CH:13][C:3]=1[O:2][CH3:1])[NH2:14])(=[O:9])[CH3:8]

참가 물질

5

반응물 2

HCID 20650534N-(2-Methoxy-5-nitrobenzyl)acetamideHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 58629454HCID 58629454, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

N-(2-Methoxy-5-nitrobenzyl)acetamide (5 g), with palladium on carbon (1 g) in ethanol (50 ml) was hydrogenated at room temperature under 104 tms. of hydrogen. The reaction was filtered through celite and the ethanol distilled from the filtrate. The residue was recrystallised from benzene to give 3-(acetylaminomethyl)-4-methoxyaniline as pale brown needles. MP; 123-125° C.

후처리

  1. customwas hydrogenated at room temperature under 104 tms
  2. filtrationThe reaction was filtered through celite
  3. distillationthe ethanol distilled from the filtrate
  4. customThe residue was recrystallised from benzene

출처 및 근거

ORD 기록
ord-2ef501d97cf64e05a715175de250eed0
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07384963B2

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