3-Acetamidobenzylamine → HCID 10225262, 화합물

HRID 131681노트

반응식

HRID 131681 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20]([OH:22])=O)=[CH:16][CH:15]=1.[NH2:23][CH2:24][C:25]1[CH:26]=[C:27]([NH:31][C:32](=[O:34])[CH3:33])[CH:28]=[CH:29][CH:30]=1>>[C:32]([NH:31][C:27]1[CH:26]=[C:25]([CH:30]=[CH:29][CH:28]=1)[CH2:24][NH:23][C:20]([C:17]1[CH:16]=[CH:15][C:14]([C:3]2[CH:4]=[C:5]([C:8]3[O:9][C:10]([CH3:13])=[N:11][N:12]=3)[CH:6]=[CH:7][C:2]=2[CH3:1])=[CH:19][CH:18]=1)=[O:22])(=[O:34])[CH3:33]

참가 물질

3

반응물 2

HCID 27609463-AcetamidobenzylamineHCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid

생성물 1

HCID 10225262HCID 10225262, 화합물

실험 절차

N-(3-Acetylaminobenzyl)-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and N-(3-aminomethylphenyl)acetamide using method H. NMR; δH [2H6]—DMSO 9.92,(1H, s), 9.15,(1H, t), 8.01,(2H, d), 7.89,(1H, dd), 7.77,(1H, d), 7.52,(5H, m), 7.23,(1H, t), 6.99,(1H, d), 4.47,(2H, d), 2.56,(3H, s), 2.32,(3H, s), 2.01,(3H, s). LCMS; retention time 2.95 min, MH+ 441.

출처 및 근거

ORD 기록
ord-0929a6c11e1e4064bfa295ce1f832f09
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07384963B2

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