Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 2-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-2-phenylacetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | methyl 2-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-2-phenylacetate | HCID 59339649 | — |
| 생성물 | 2-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-2-phenylacetamide | HCID 59339722 | — |
반응 단계
A suspension of methyl 2-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-2-phenylacetate (137c, 75 mg, 200 μmol) in methanolic NH3 (7 M, 1 ml) was stirred at r.t. overnight to give a clear solution. Then the solvent was removed in vacuo, and the crude product was freeze-dried go give white solid material, 60 mg (83%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728030B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-81d60e2148214d4e864b058f4eaadea7 |
| 출처 메모 | uspto-grants-2010_06 |