4-(Aminomethyl)benzonitrile → HCID 10272850, 화합물

HRID 131691

반응식

HRID 131691 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[C:23]([C:25]1[CH:32]=[CH:31][C:28]([CH2:29][NH2:30])=[CH:27][CH:26]=1)#[N:24]>>[C:23]([C:25]1[CH:32]=[CH:31][C:28]([CH2:29][NH:30][C:20]([C:17]2[CH:18]=[CH:19][C:14]([C:3]3[CH:4]=[C:5]([C:8]4[O:9][C:10]([CH3:13])=[N:11][N:12]=4)[CH:6]=[CH:7][C:2]=3[CH3:1])=[CH:15][CH:16]=2)=[O:21])=[CH:27][CH:26]=1)#[N:24]

참가 물질

3

반응물 2

HCID 826084-(Aminomethyl)benzonitrileHCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid

생성물 1

HCID 10272850HCID 10272850, 화합물

실험 절차

N-(4-Cyanobenzyl)-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-cyanobenzylamine using method N. NMR; δH [2H6]—DMSO 9.25,(1H, t), 8.01,(2H, d), 7.90,(1H, dd), 7.81,(2H, d), 7.77,(1H, d), 7.56-7.51,(5H, m), 4.58,(2H, d), 2.56,(3H, s), 2.31,(3H, s). LCMS; retention time 3.34 min, MH+ 409.

출처 및 근거

ORD 기록
ord-960edf85af8a445dbf73fa688d985b60
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07384963B2

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