2-Methylbenzylamine → HCID 10222443, 화합물

HRID 131711

반응식

HRID 131711 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20]([OH:22])=O)=[CH:16][CH:15]=1.[CH3:23][C:24]1[CH:31]=[CH:30][CH:29]=[CH:28][C:25]=1[CH2:26][NH2:27]>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:15]=[CH:16][C:17]([C:20]([NH:27][CH2:26][C:25]2[CH:28]=[CH:29][CH:30]=[CH:31][C:24]=2[CH3:23])=[O:22])=[CH:18][CH:19]=1

참가 물질

3

반응물 2

HCID 69932-MethylbenzylamineHCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid

생성물 1

HCID 10222443HCID 10222443, 화합물

실험 절차

2′-Methyl-N-(2-methylbenzyl)-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 2-methylbenzylamine using method N. NMR; δH [2H6]—DMSO 9.01,(1H, t), 8.01,(2H, d), 7.90,(1H, dd), 7.77,(1H, d), 7.56-7.51,(3H, m), 7.26,(1H, m), 7.18-7.15,(3H, m), 4.48,(2H, d), 2.56,(3H, s), 2.33,(3H, s), 2.31,(3H, s). LCMS; retention time 3.47 min, MH+ 398.

출처 및 근거

ORD 기록
ord-43b17ebee4a1443a9c5882ce4c721488
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07384963B2

연결된 노트

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