Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → Benzene, 1-fluoro-2-[(2-nitrophenyl)thio]-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 반응물 | 2-Fluorothiophenol | HCID 520216 | — |
| 반응물 | 2-(2-Fluorophenylsulfanyl)aniline | HCID 11850357 | — |
| 생성물 | Benzene, 1-fluoro-2-[(2-nitrophenyl)thio]- | HCID 11850287 | 83% |
| 생성물 | HCID 59733001 | HCID 59733001 | 75% |
반응 단계
2-(2-Fluorophenylsulfanyl)nitrobenzene (1.03 g, 83%) was prepared from 2-fluorothiophenol (0.70 g, 5.5 mmol) and 2-fluoronitrobenzene (0.71 g, 5.0 mmol) following the general procedure A. This compound was reduced to 2-(2-fluorophenylsulfanyl)aniline (0.65 g, 72%) following general procedure B. N-[2-(2-Fluorophenylsulfanyl)phenyl]-N′-(thiazol-2-yl)urea (129 mg, 75%) was prepared from 2-(2-fluorophenylsulfanyl)aniline (107 mg, 0.5 mmol) and 2-aminothiazole (60 mg, 0.6 mmol) following the general procedure D.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07384967B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-782ed4d5a4c34964901422f06cd6ca0d |
| 출처 메모 | uspto-grants-2008_06 |