Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → 2-(Cyclopentylmethoxy)-1-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 반응물 | Cyclopentanemethanol | HCID 77195 | — |
| 반응물 | 2-(Cyclopentylmethoxy)aniline | HCID 19754712 | — |
| 생성물 | N-[2-(Cyclopentylmethoxy)phenyl]-N'-(thiazol-2-yl)urea | HCID 59732720 | 60% |
| 생성물 | 2-(Cyclopentylmethoxy)-1-nitrobenzene | HCID 66998904 | 80% |
반응 단계
2-(Cyclopentylmethoxy)-1-nitrobenzene (443 mg, 80%) was prepared from cyclopentanemethanol (0.32 ml, 3.0 mmol) and 1-fluoro-2-nitrobenzene (0.36 g, 2.5 mmol) following the general procedure G. This was reduced to 2-(cyclopentylmethoxy)aniline (268 mg, 70%) following general procedure B. N-[2-(Cyclopentylmethoxy)phenyl]-N′-(thiazol-2-yl)urea (286 mg, 60%) was prepared from 2-(cyclopentylmethoxy)aniline (0.25 g, 1.5 mmol) and 2-aminothiazole (150 mg, 1.5 mmol) following the general procedure D.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07384967B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-92b0c447208c44e08a1489467c195453 |
| 출처 메모 | uspto-grants-2008_06 |