반응식
[F:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]1([CH2:15][C:16](=[O:20])[C:17](O)=[O:18])[CH2:14][CH2:13]1.[NH2:21][C:22]1[CH:23]=[C:24]2[C:29](=[CH:30][CH:31]=1)[C:27](=[O:28])[O:26][CH2:25]2>>[F:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]1([CH2:15][C:16](=[O:20])[C:17]([NH:21][C:22]2[CH:23]=[C:24]3[C:29](=[CH:30][CH:31]=2)[C:27](=[O:28])[O:26][CH2:25]3)=[O:18])[CH2:13][CH2:14]1참가 물질
3
실험 절차
Preparation from 3-[1-(2-fluoro-3-trifluoromethylphenyl)-cyclopropyl]-2-oxo-propionic acid and 5-aminophthalide analogously to the preparation of 5-{3-[1-(2-fluoro-5-trifluoromethylphenyl)-cyclopropyl]-2-oxo-propionylamino}-phthalide (cf. Example 1a)). M.p. 157-158° C.
후처리
- customanalogously to the preparation of 5-{3-[1-(2-fluoro-5-trifluoromethylphenyl)-cyclopropyl]-2-oxo-propionylamino}-phthalide (cf. Example 1a))
출처 및 근거
- ORD 기록
- ord-d54ecfbcb7874a0dbf0b69b2c808a283
- 출처 데이터셋
- uspto-grants-2008_06
- 특허 번호
- US07388006B2
연결된 노트
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