PyBroP → 4-(2-((2s,3s)-2-Acetyl-3-(tert-butyldimethylsilyloxy)pyrrolidin-1-yl)-2-oxoethyl)-2-chloro-3-methylbenzonitrile

반응식

C(O[C:6]([N:8]1[CH2:12][CH2:11][C@H:10]([O:13][Si:14]([C:17]([CH3:20])([CH3:19])[CH3:18])([CH3:16])[CH3:15])[C@@H:9]1[CH:21]([OH:23])[CH3:22])=[O:7])(C)(C)C.C(O)(C(F)(F)F)=O.C(Cl)Cl.C1CN([P+](Br)(N2CCCC2)N2CCCC2)CC1.F[P-](F)(F)(F)(F)F.[Cl:58][C:59]1[C:60]([CH3:71])=[C:61]([CH2:67]C(O)=O)[CH:62]=[CH:63][C:64]=1[C:65]#[N:66]>C(Cl)Cl.C1COCC1.CCOC(C)=O.C1(C)C=CC=CC=1>[C:21]([C@@H:9]1[C@@H:10]([O:13][Si:14]([C:17]([CH3:18])([CH3:19])[CH3:20])([CH3:15])[CH3:16])[CH2:11][CH2:12][N:8]1[C:6](=[O:7])[CH2:67][C:61]1[CH:62]=[CH:63][C:64]([C:65]#[N:66])=[C:59]([Cl:58])[C:60]=1[CH3:71])(=[O:23])[CH3:22]