Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → 4-Methylheptane-3,5-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 3,5-Heptanedione | HCID 81923 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Methylheptane-3,5-dione | HCID 3013982 | 94% |
반응 단계
To 0.02 mol sodium hydride was added 100 ml anhydrous tetrahydrofuran, slowly added dropwise 0.02 mol 3,5-heptandione at room temperature. Upon completion, the mixture was stirred for 0.5 hours, then 0.04 mol iodomethane was slowly added dropwise. After stirred at room temperature for 10 hours, 20 ml water was added. White solid was precipitated. The solid was filtered, washed with water, and dried to give 4-methyl-3,5-heptandione as a white solid, and the yield was 94%. m.p. was 91-92° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07388061B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-215ad9bed3a34087a85ae1671f74959f |
| 출처 메모 | uspto-grants-2008_06 |