돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 132817생성일: 2026년 10월 26일

5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acid ethyl ester → 5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/132817

반응식

참여 물질

역할이름HCID투입량
반응물5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acid ethyl esterHCID 45112356—
반응물[5-Hydroxy-1-(2,2,2-trifluoro-ethyl)-1H-indol-2-yl]-morpholin-4-yl-methanoneHCID 67527268—
생성물5-(3-Chloro-propoxy)-1H-indole-2-carboxylic acidHCID 67526619—

반응 단계

In analogy to the procedure described for the synthesis of intermediate 1, step 3, the title compound was synthesized from 5-(3-chloro-propoxy)-1H-indole-2-carboxylic acid ethyl ester (example 4, step 1). The title compound was obtained in 98% yield as white solid. MS (m/e): 252.9 (M−H−, 100%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07388095B2
출처 데이터셋uspto-grants-2008_06
ORD IDord-1f648f46653546e88c7464e7232e9449
출처 메모uspto-grants-2008_06