Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine → Pyrazine, 2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-[(2,4,5-trifluorophenyl)methyl]-, (2S,5R)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine | HCID 736065 | — |
| 반응물 | 2,4,5-Trifluorobenzyl Bromide | HCID 2777057 | — |
| 생성물 | Pyrazine, 2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-[(2,4,5-trifluorophenyl)methyl]-, (2S,5R)- | HCID 11290377 | 62.7% |
반응 단계
The title compound (3.81 g) was prepared from 3.42 g (18.5 mmol) of (2S)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazine and 5 g (22.3 mmol) of 2,4,5-trifluorobenzyl bromide using the procedure described for Intermediate 2, Step A.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07388019B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-540da271cfc542548cd906ed04797527 |
| 출처 메모 | uspto-grants-2008_06 |