Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 2-(trifluoromethyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 6-(tert-Butoxycarbonyl)-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine | HCID 69223721 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-(trifluoromethyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine | HCID 53471483 | — |
반응 단계
Reaction of the product from Step A above with trifluoroacetic acid in dichloromethane according to the procedure outlined for Intermediate 28, Step C afforded the title compound as a white powder. LC/MS 204.0 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07388019B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-cc45c23990ba456899627ba7fa8afba1 |
| 출처 메모 | uspto-grants-2008_06 |