Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, trifluoroacetate salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | tert-Butyl 2-methyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate | HCID 69223447 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, trifluoroacetate salt | HCID 131726931 | — |
반응 단계
Reaction of the product from Step A above with trifluoroacetic acid in dichloromethane according to the procedure outlined for Intermediate 28, Step C afforded the title compound as a light orange powder. LC/MS 150.1 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07388019B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-6e4a4110fd734a84b43ed6b6d96031e2 |
| 출처 메모 | uspto-grants-2008_06 |