Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Pyrazinecarboxylic acid → 2-Fluoropyridin-3-yloxy-6-(6-methanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| 반응물 | 2-Fluoropyridin-3-yloxy-6-(6-methanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 86619207 | — |
| 생성물 | 2-Fluoropyridin-3-yloxy-6-(6-methanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole | HCID 86619206 | — |
반응 단계
The entitled compound was obtained as a colorless solid in the same method as in Example 197 or in accordance with the method or by combining it with an ordinary method but using 4-(2-fluoro-pyridin-3-yloxy)-5-(6-methanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 211 and pyrazine-2-carboxylic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728025B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-194fb255b7a642aa952b8ba73856e40a |
| 출처 메모 | uspto-grants-2010_06 |